The Mercedes-Benz E 450 4MATIC All-Terrain Wagon is a top of range variant of the Mercedes-Benz X213. The E450 4MATIC All-Terrain Wagon was powered by a turbocharged 3.0L inline six 'M256 engine, producing 389hp and 369 lb⋅ft. This engine was paired to a 48V integrated starter-generator adding an extra 23hp and 151 lb⋅ft for a combined output of 412hp and 520 lb⋅ft. Drive was sent to all four wheels via an 9G-Tronic 9-speed automatic transmission. The E450 4MATIC All-Terrain Wagon was replaced by the X214 E450 4MATIC All-Terrain Wagon in 2024.